![]() ![]() To address these and other needs of chronic wounds, frequently standard wound care (SWC) is employed alone or in combination with adjunctive wound treatments that deliver several types of biophysical energy to further enhance wound healing. 2 During the past two decades, numerous wound interventions have been developed to facilitate healing by addressing maintenance of wound moisture, reduction of bacterial and nonviable tissue burdens, and management of cytokines and proteases and by stimulating expression of growth factors. 1, 2 The encumbrance of treating chronic wounds is increasing rapidly owing to increasing healthcare costs, an aging population, and, in the United States and many other countries, the incidence of diabetes and obesity is increasing precipitously. healthcare system, involving 5.7–6.5 million patients and costing an estimated 20–25 billion dollars annually. Microfluidic wound-healing chips are currently being used with greater accuracy to investigate the EF effects on cellular electrotaxis.Ĭonclusion: Numerous clinical trials described in subsequent sections of this issue have demonstrated that ES used adjunctively with standard wound care (SWC), enhances wound healing rate faster than SWC alone.Ĭ hronic wounds represent a major problem to patients, healthcare professionals, and the U.S. Innovation: Wafer-thin, disposable ES technologies (wound dressings) that utilize mini or micro-batteries to deliver low-level DC for wound healing and antibacterial wound-treatment purposes are commercially available. Results: Commercial ES devices that generate direct current (DC), and mono and biphasic pulsed current waveforms represent the principal ES technologies which are reported to enhance wound healing. Objective: To discuss the physiological bases for using exogenously applied electric field (EF) energy to enhance wound healing with conductive electrical stimulation (ES) devices.Īpproach: To describe the types of electrical currents that have been reported to enhance chronic wound-healing rate and closure. ![]()
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